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anti mouse cd96  (Bio X Cell)


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    Structured Review

    Bio X Cell anti mouse cd96
    Anti Mouse Cd96, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 95/100, based on 66 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/invivomab+anti+mouse+cd96/pm41382272-1078-262-268?v=Bio+X+Cell
    Average 95 stars, based on 66 article reviews
    anti mouse cd96 - by Bioz Stars, 2026-07
    95/100 stars

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    Bio X Cell invivomab anti mouse cd96
    CD226 signaling is indispensable for IFNγ production from NK cells (A) Intravenous mouse model of 4T1 control or Pvr + metastasis in Il22 −/− mice. Animals received injections of anti-CD226 blocking antibody (420.1, 200 μg per mouse) or control i.p. on days 0, 3, and 14. (B) Numbers of macroscopic lung metastases and colonies in metastasis assay. (C) IFNγ-producing NK cells in the lungs evaluated by flow cytometry. Data presented as means ± SEM; p values <0.05 were considered significant by the Mann-Whitney U test. (D) Representative dot plots depict CD226 low, medium, and high NK cells. Frequency of IFNγ+ cells among NK cell populations (n = 5–6). Numbers represent the frequency of the parent gate. Data presented as means ± SEM; p values <0.05 were considered significant by the two-way ANOVA. (E) Intravenous mouse model of 4T1 control or Pvr + lung metastasis in Il22 −/− mice. Animals received injections of anti-TIGIT agonist antibody (1G9, 250 μg per mouse), <t>anti-CD96</t> blocking antibody (3.3, 250 μg per mouse), or control i.p. on days 0, 3, and 14. (F) Numbers of macroscopic lung metastases. (G) IFNγ-producing NK and CD8 + T cells in the lungs were evaluated by flow cytometry. Numbers represent the frequency of the parent gate. Data presented as means ± SEM; p values <0.05 were considered significant by unpaired t- test (n = 5–6).
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    Average 94 stars, based on 1 article reviews
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    Bio X Cell soluble anti cd3 antibody
    CD226 signaling is indispensable for IFNγ production from NK cells (A) Intravenous mouse model of 4T1 control or Pvr + metastasis in Il22 −/− mice. Animals received injections of anti-CD226 blocking antibody (420.1, 200 μg per mouse) or control i.p. on days 0, 3, and 14. (B) Numbers of macroscopic lung metastases and colonies in metastasis assay. (C) IFNγ-producing NK cells in the lungs evaluated by flow cytometry. Data presented as means ± SEM; p values <0.05 were considered significant by the Mann-Whitney U test. (D) Representative dot plots depict CD226 low, medium, and high NK cells. Frequency of IFNγ+ cells among NK cell populations (n = 5–6). Numbers represent the frequency of the parent gate. Data presented as means ± SEM; p values <0.05 were considered significant by the two-way ANOVA. (E) Intravenous mouse model of 4T1 control or Pvr + lung metastasis in Il22 −/− mice. Animals received injections of anti-TIGIT agonist antibody (1G9, 250 μg per mouse), <t>anti-CD96</t> blocking antibody (3.3, 250 μg per mouse), or control i.p. on days 0, 3, and 14. (F) Numbers of macroscopic lung metastases. (G) IFNγ-producing NK and CD8 + T cells in the lungs were evaluated by flow cytometry. Numbers represent the frequency of the parent gate. Data presented as means ± SEM; p values <0.05 were considered significant by unpaired t- test (n = 5–6).
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    CD226 signaling is indispensable for IFNγ production from NK cells (A) Intravenous mouse model of 4T1 control or Pvr + metastasis in Il22 −/− mice. Animals received injections of anti-CD226 blocking antibody (420.1, 200 μg per mouse) or control i.p. on days 0, 3, and 14. (B) Numbers of macroscopic lung metastases and colonies in metastasis assay. (C) IFNγ-producing NK cells in the lungs evaluated by flow cytometry. Data presented as means ± SEM; p values <0.05 were considered significant by the Mann-Whitney U test. (D) Representative dot plots depict CD226 low, medium, and high NK cells. Frequency of IFNγ+ cells among NK cell populations (n = 5–6). Numbers represent the frequency of the parent gate. Data presented as means ± SEM; p values <0.05 were considered significant by the two-way ANOVA. (E) Intravenous mouse model of 4T1 control or Pvr + lung metastasis in Il22 −/− mice. Animals received injections of anti-TIGIT agonist antibody (1G9, 250 μg per mouse), anti-CD96 blocking antibody (3.3, 250 μg per mouse), or control i.p. on days 0, 3, and 14. (F) Numbers of macroscopic lung metastases. (G) IFNγ-producing NK and CD8 + T cells in the lungs were evaluated by flow cytometry. Numbers represent the frequency of the parent gate. Data presented as means ± SEM; p values <0.05 were considered significant by unpaired t- test (n = 5–6).

    Journal: Immunity

    Article Title: T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis

    doi: 10.1016/j.immuni.2022.12.010

    Figure Lengend Snippet: CD226 signaling is indispensable for IFNγ production from NK cells (A) Intravenous mouse model of 4T1 control or Pvr + metastasis in Il22 −/− mice. Animals received injections of anti-CD226 blocking antibody (420.1, 200 μg per mouse) or control i.p. on days 0, 3, and 14. (B) Numbers of macroscopic lung metastases and colonies in metastasis assay. (C) IFNγ-producing NK cells in the lungs evaluated by flow cytometry. Data presented as means ± SEM; p values <0.05 were considered significant by the Mann-Whitney U test. (D) Representative dot plots depict CD226 low, medium, and high NK cells. Frequency of IFNγ+ cells among NK cell populations (n = 5–6). Numbers represent the frequency of the parent gate. Data presented as means ± SEM; p values <0.05 were considered significant by the two-way ANOVA. (E) Intravenous mouse model of 4T1 control or Pvr + lung metastasis in Il22 −/− mice. Animals received injections of anti-TIGIT agonist antibody (1G9, 250 μg per mouse), anti-CD96 blocking antibody (3.3, 250 μg per mouse), or control i.p. on days 0, 3, and 14. (F) Numbers of macroscopic lung metastases. (G) IFNγ-producing NK and CD8 + T cells in the lungs were evaluated by flow cytometry. Numbers represent the frequency of the parent gate. Data presented as means ± SEM; p values <0.05 were considered significant by unpaired t- test (n = 5–6).

    Article Snippet: InVivoMAb anti-mouse CD96 (3.3) , BioXCell , Cat# BE0337; RRID: AB_2894757.

    Techniques: Control, Blocking Assay, Flow Cytometry, MANN-WHITNEY

    Journal: Immunity

    Article Title: T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis

    doi: 10.1016/j.immuni.2022.12.010

    Figure Lengend Snippet:

    Article Snippet: InVivoMAb anti-mouse CD96 (3.3) , BioXCell , Cat# BE0337; RRID: AB_2894757.

    Techniques: Purification, Control, Virus, Recombinant, Red Blood Cell Lysis, Transfection, Flow Cytometry, DNA Extraction, Gel Extraction, Plasmid Preparation, cDNA Synthesis, Cell Differentiation, Staining, Cell Isolation, Conjugation Assay, Sequencing, CRISPR, Retroviral, Software